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Acute Respiratory Distress Syndrome: Colloquium Series on Integrated Systems Physiology: From Molecule to Function

Autor Marie C. Elie, Donna Carden
en Limba Engleză Paperback – oct 2013
The acute respiratory distress syndrome (ARDS) is a complex disorder associated with rapidly progressive lung inflammation, non-cardiogenic pulmonary edema, hypoxemic respiratory failure and one or more well-defined risk factors including sepsis and severe trauma. Since its original description in 1967, experimental and clinical evidence has provided considerable insight into the key roles deregulated systemic inflammation and coagulation play in this devastating clinical syndrome. Despite substantial advances in our understanding of the pathogenesis of ARDS, until recently, little progress had been made in uncovering clinical strategies to improve the outcome of patients with ARDS. However, over the past 10 years protective ventilation and other supportive management strategies have been identified that markedly improve the outcome in ARDS. More recently, research has identified patients at risk for the development of the syndrome. Currently, clinical trials are underway. Table of Contents: Introduction / The Pathogenesis of ARDS / Experimental Models of ARDS / Resolution, Treatment, and Prevention of ARDS / References
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Specificații

ISBN-13: 9781615046348
ISBN-10: 1615046348
Pagini: 100
Dimensiuni: 191 x 235 x 5 mm
Greutate: 0.19 kg
Editura: Morgan & Claypool
Seria Colloquium Series on Integrated Systems Physiology: From Molecule to Function


Descriere

The acute respiratory distress syndrome (ARDS) is a complex disorder associated with rapidly progressive lung inflammation, non-cardiogenic pulmonary edema, hypoxemic respiratory failure and one or more well-defined risk factors including sepsis and severe trauma. Since its original description in 1967, experimental and clinical evidence has provided considerable insight into the key roles deregulated systemic inflammation and coagulation play in this devastating clinical syndrome. Despite substantial advances in our understanding of the pathogenesis of ARDS, until recently, little progress had been made in uncovering clinical strategies to improve the outcome of patients with ARDS. However, over the past 10 years protective ventilation and other supportive management strategies have been identified that markedly improve the outcome in ARDS. More recently, research has identified patients at risk for the development of the syndrome. Currently, clinical trials are underway. Table of Contents: Introduction / The Pathogenesis of ARDS / Experimental Models of ARDS / Resolution, Treatment, and Prevention of ARDS / References